Follow the instructions exactly about when to stop eating and drinking, or your surgery may be canceled. If your doctor has instructed you to take your medicines on the day of surgery, please do so using only a sip of water. Had abdominal surgeries in the past. Statins such as atorvastatin are usually well-tolerated. If side effects do occur, your doctor might lower your dose to see if the side effect will subside. They generally resolve within a few hours after taking the dose, but recurrence has been frequently reported with subsequent doses. Instruct patients to contact their healthcare provider if dyspnea occurs.
During a 7-week randomized withdrawal study, patients who received Amitiza during a 4-week treatment period were then randomized to receive either placebo or to continue treatment with Amitiza. In Amitiza-treated patients randomized to placebo, SBM frequency rates returned toward baseline within 1 week and did not result in worsening compared to baseline. Patients who continued on Amitiza maintained their response to therapy over the additional 3 weeks of treatment. For patients with moderately impaired hepatic function Child-Pugh Class B the recommended starting dose is 16 mcg twice daily. For patients with severely impaired hepatic function Child-Pugh Class C the recommended starting dose is 8 mcg twice daily.
What is ulcerative colitis? CoQ10 supplements on your own, however. Work with your doctor when you take any supplement. Use Lipitor as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage. Eating grapefruit or drinking grapefruit juice may increase the amount of Lipitor in your blood, which may increase your risk for serious side effects. The risk may be greater with large amounts of grapefruit or grapefruit juice. Avoid large amounts of grapefruit or grapefruit juice eg, more than 1 quart daily. Talk with your doctor or pharmacist if you have questions about including grapefruit or grapefruit juice in your diet while you are taking Lipitor. Lipitor is an HMG-CoA reductase inhibitor, also known as a "statin.
Additionally, in vitro studies in human liver microsomes demonstrate that lubiprostone does not inhibit cytochrome P450 isoforms 3A4, 2D6, 1A2, 2A6, 2B6, 2C9, 2C19, or 2E1, and in vitro studies of primary cultures of human hepatocytes show no induction of cytochrome P450 isoforms 1A2, 2B6, 2C9, and 3A4 by lubiprostone. Partial removal resection of the also can be done. Crohn's can affect any part of the digestive tract. For every 5 to 10 grams that you add to your diet, you can lower your levels by up to 5%. Try to get at least 25 to 30 grams of total fiber a day. Most fruits, vegetables, and oats have both soluble and insoluble fiber. Continue to take Lipitor even if you feel well. Do not miss any doses. Continued How is it treated? In this test, a doctor uses a thin, lighted tool to look at the inside of your entire colon. At the same time, the doctor may take a sample of the lining of the colon. The FDA approved a 40-milligram dose for people with relapsing-remitting MS. The 20-milligram daily dose will still be available. The suit filed by Michael Mazzariello, a 47-year-old New Yorker, says his use of -- the family of -lowering drugs to which Lipitor belongs -- left him with debilitating muscle damage and extensive memory loss. Nausea: Approximately 29% of patients who received Amitiza 24 mcg twice daily experienced nausea; 4% of patients had severe nausea and 9% of patients discontinued treatment due to nausea. The rate of nausea associated with Amitiza 24 mcg twice daily was lower among male 8% and elderly 19% patients. No patients in the clinical studies were hospitalized due to nausea. These drugs may increase the risk of bleeding problems if taken during treatment with warfarin. June 9, 2006 - Lawsuits filed this week claim that drug-maker Pfizer has failed to warn doctors and patients about serious possible side effects of the -lowering drug. Atorvastatin Side Effects: What Should I Know? Moderate. These medicines may cause some risk when taken together. There are many other drugs that can increase your risk of serious medical problems if you take them together with atorvastatin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. Call for most recent medications as the list is subject to change and the medication for which you are seeking assistance must treat the disease directly. Note: All new enrollment is now done electronically or over the phone. Contact program for details.
No reports of toxicity have been reported following ingestion of large amounts of turmeric. Diarrhea: Approximately 8% of patients who received Amitiza 24 mcg twice daily experienced diarrhea; 2% of patients had severe diarrhea and 1% of patients discontinued treatment due to diarrhea. The longer you have had ulcerative colitis, the greater your risk. Talk to your doctor about your need for screening. These tests help find early, when it is easier to treat. Lipitor may cause liver problems. Rarely, severe and sometimes fatal liver problems have been reported in patients taking "statin" medicines, including Lipitor. Your risk of developing liver problems may be greater if you drink alcohol daily or in large amounts, or if you have a history of liver problems. Check with your doctor before drinking alcohol while you are taking Lipitor. Tell your doctor right away if you experience symptoms of liver problems eg, dark urine; pale stools; severe or persistent nausea, loss of appetite, or stomach pain; unusual tiredness; yellowing of the skin or eyes. Safety and effectiveness in pediatric patients have not been established. Amitiza 24 mcg twice daily or placebo twice daily for 4 weeks. The primary endpoint of the studies was SBM frequency. The studies demonstrated that patients treated with Amitiza had a higher frequency of SBMs during Week 1 than the placebo patients. Overall, the risks of taking statins are very low -- lower than the risks from taking two a day, McBride says. Milani says. "I am talking about the many people having no problem while taking these drugs. Jacobson TA. Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors. aripiprazole
Lubiprostone, via activation of apical ClC-2 channels in intestinal epithelial cells, bypasses the antisecretory action of opiates that results from suppression of secretomotor neuron excitability. Some people take along with statins, or -- if their cholesterol isn't too high -- instead of them. There's good evidence that some can help with cholesterol levels. Store at room temperature away from moisture, heat, and light. Teva Pharmaceutical Industries, says the three-times-per-week regimen “will be available to patients within days. Contact your doctor or pharmacist if you miss 2 or more doses in a row. Avoid use of Amitiza in patients with severe diarrhea. Patients should be aware of the possible occurrence of diarrhea during treatment. Baycol was removed from the market in 2001 because it caused far more cases of muscle damage than other members of its class. Livalo pitavastatin US prescribing information. Kowa Pharmaceuticals America, Inc. October, 2013. Adhesions, cysts, or abnormal growths, such as tumors, may be seen. This information should not be used to decide whether or not to take Lipitor or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Lipitor. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Lipitor. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Lipitor. If you miss a dose of Lipitor, take it as soon as possible if you remember within 12 hours of the missed dose. If it is more than 12 hours since the missed dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. best price brand arava arava
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. If you have other types of anesthesia, you may have pain for a few days when the initial numbness wears off. Lab tests, including blood cholesterol levels, creatine phosphokinase CPK levels, and liver function, may be performed while you use Lipitor. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. How is Atorvastatin Dosage Determined? Lipitor, one of the best selling drugs of all time. It works by reducing the production of certain fatty substances in the body, including cholesterol. Have to any medicines, including anesthesia.
FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not take atorvastatin if you are pregnant. Stop taking this medication and tell your doctor right away if you become pregnant. Use effective birth control to avoid pregnancy while you are taking atorvastatin. How can I get my LDL or bad cholesterol under control? Posted 2 days 22 hours ago by Drugs. Reference Listed Drug RLD is an approved drug product to which new generic versions are compared to show that they are bioequivalent. A drug company seeking approval to market a generic equivalent must refer to the Reference Listed Drug in its Abbreviated New Drug Application ANDA. By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart. During a 4-week randomized withdrawal period following Study 1, patients who received Amitiza during the 12-week treatment period were re-randomized to receive either placebo or to continue treatment with Amitiza. In Amitiza-treated patients who were "overall responders" during Study 1 and who were re-randomized to placebo, SBM frequency rates did not result in worsening compared to baseline. In vitro studies using human liver microsomes indicate that cytochrome P450 isoenzymes are not involved in the metabolism of lubiprostone. Take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 12 hours away. Do not take extra medicine to make up the missed dose. When these two medicines are taken together, your body may not process your cholesterol medicine properly. ipan.info toprol
Electrolytes: No serious adverse reactions of electrolyte imbalance were reported in clinical studies, and no clinically significant changes were seen in serum electrolyte levels in patients receiving Amitiza. Very-low-density lipoprotein VLDL cholesterol level. The primary efficacy analysis was a comparison of the proportion of "overall responders" in each arm. A patient was considered an "overall responder" if the criteria for being designated a "monthly responder" were met in at least 2 of the 3 months on study. A "monthly responder" was defined as a patient who had reported "significantly relieved" for at least 2 weeks of the month or at least "moderately relieved" in all 4 weeks of that month. During each monthly evaluation period, patients reporting "moderately worse" or "significantly worse" relief, an increase in rescue medication use, or those who discontinued due to lack of efficacy, were deemed non-responders. Patients had been receiving stable opioid therapy for at least 30 days prior to screening, which was to continue throughout the 12-week treatment period. At baseline, mean oral morphine equivalent daily doses MEDDs were 99 mg and 130 mg for placebo-treated and Amitiza-treated patients, respectively, in Study 1. Baseline mean MEDDs were 237 mg and 265 mg for placebo-treated and Amitiza-treated patients, respectively, in Study 2. In Study 3, baseline mean MEDDs were 330 mg and 373 mg for placebo-treated and Amitiza-treated patients, respectively. The Brief Pain Inventory-Short Form BPI-SF questionnaire was administered to patients at baseline and monthly during the treatment period to assess pain control. What is atorvastatin Lipitor? Patent and Trademark Office at any time during a drug's development and may include a wide range of claims. Physicians and patients should periodically assess the need for continued therapy. This list is not complete and there are many other drugs that can increase your risk of serious medical problems if you take them together with atorvastatin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. M3 increases dose proportionally after single 24-mcg and 144-mcg doses of lubiprostone. Avoid getting injections into the muscles. If you must have an injection into a muscle for example, a it should be given in the arm. Patients must have health insurance and their insurance must cover the qualifying medication for which they seek assistance. And the report notes that the link between statins and peripheral neuropathy is "putative. Be sure to tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the names of all of the medicines you take. Keep a list of them with you to show your doctor and pharmacist. donepezil vs 24 hour
Exclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant. Store Lipitor at room temperature, between 68 and 77 degrees F 20 and 25 degrees C. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lipitor out of the reach of children and away from pets. Muscle problems may range from soreness, pain, cramping and tenderness to rare muscle effects like rhabdomyolysis, a severe muscle breakdown that can lead to kidney failure. Certain drug interactions may increase the risk for muscle effects. To be sure this medicine is helping your condition, your blood will need to be tested often. Visit your doctor regularly. It is important that all your doctors and dentists know that you take warfarin. The reasons for that aren't clear. IBS-C respond differently to Amitiza from women. Gengraf, Neoral, Sandimmune sirolimus Rapamune or tacrolimus Prograf. Patent and Trademark Office and assigns exclusive legal right to the patent holder to protect the proprietary chemical formulation. The patent assigns exclusive legal right to the inventor or patent holder, and may include entities such as the drug brand name, trademark, product dosage form, ingredient formulation, or manufacturing process A patent usually expires 20 years from the date of filing, but can be variable based on many factors, including development of new formulations of the original chemical, and patent infringement litigation. Amitiza is available as an oval, soft gelatin capsule containing 8 mcg or 24 mcg of lubiprostone with "SPI" printed on one side. IBS-C were nausea, diarrhea, and abdominal pain. Your doctor may talk to you about the surgery once you are fully awake. He or she may call you at home later to talk to you about the results. Results of any lab tests on tissue samples may not be available for several days. Diarrhea: Approximately 12% of patients who received Amitiza 24 mcg twice daily experienced diarrhea; 2% of patients had severe diarrhea and 2% of patients discontinued treatment due to diarrhea. Lubiprostone is a locally acting chloride channel activator that enhances a chloride-rich intestinal fluid secretion without altering sodium and potassium concentrations in the serum. Elderly patients taking Amitiza 24 mcg twice daily experienced a lower rate of associated nausea compared to the overall study population taking Amitiza 19% vs. 29%, respectively.
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. More than 20 million patients have taken the drug since it entered the market about a decade ago. Any potential side effects, any significant adverse events are on the drug's label, in our advertisements, and on our web site. To say we have hidden information on this drug is absolutely false. New MS lesions in the were also significantly lower in people taking the higher dose of Copaxone. Lipitor. I could not take any of the other statins for longer than 2 weeks. I had pain throughout my body. Tried Lipitor in a low dose 10mg. In 6 weeks I started getting same problems with pain. I am tired, don't feel like working out, weak, irritable. My joints hurt and I feel weak in general. Need to pee more often. The gas used during the laparoscopy can irritate your for a few days. You may have some pain or achiness in your for a couple of days after the laparoscopy. Less common adverse reactions: The following adverse reactions assessed by investigator as probably or definitely related to treatment occurred in less than 1% of patients receiving Amitiza 24 mcg twice daily in clinical studies, occurred in at least two patients, and occurred more frequently in patients receiving study drug than those receiving placebo: fecal incontinence, muscle cramp, defecation urgency, frequent bowel movements, hyperhidrosis, pharyngolaryngeal pain, intestinal functional disorder, anxiety, cold sweat, constipation, cough, dysgeusia, eructation, influenza, joint swelling, myalgia, pain, syncope, tremor, decreased appetite. HDL levels, the “good” cholesterol. People in most studies showing a benefit have taken 1 to 4 grams of a day. No contraindications have been determined. Can Generic Manufacturers Be Trusted? The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Sometimes these news stories about lawsuits scare people. You may be asked to use an or several hours before or the day before the surgery to empty your colon. pristiq protect price
Muscle problems myopathy may occur with Lipitor. Report any unexplained muscle pain, tenderness, or weakness to your doctor right away, especially if you also have a fever or general body discomfort. Tell your doctor if you have muscle problems that persist even after your doctor has told you to stop taking Lipitor. The lawsuits prominently claim that Lipitor caused in the plaintiffs. In rare cases, atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism underactive thyroid. To get your cholesterol down to lower your risk of cardiovascular disease your doctor may recommend, though, that you still need a statin. These powerful cholesterol-lowering medicines include and among others. If you have any questions about Lipitor, please talk with your doctor, pharmacist, or other health care provider. Less common adverse reactions: The following adverse reactions assessed by investigator as probably or definitely related to treatment occurred in less than 1% of patients receiving Amitiza 24 mcg twice daily in clinical studies, occurred in at least two patients, and occurred more frequently in patients receiving study drug than those receiving placebo: fecal incontinence, blood potassium decreased. The primary efficacy analysis was a comparison of the proportion of "overall responders" in each treatment arm. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Women, especially, should watch for symptoms. They are more likely to get bladder infections than men are. cefaclor
Although substandard quality control issues can be alarming for the public, most US generic manufacturers can be trusted to produce equivalent generic substitutions due to regulatory oversight from FDA. In fact, it is the that halted the Ranbaxy shipments. In addition, many other manufacturers also make high-quality versions generic atorvastatin. When you take a statin, you do more than improve your cholesterol levels. Pfizer. But now the consumer is reaping the rewards; the generic version can a patient literally hundreds in health care dollars per month. Now that as atorvastatin, along with many other statins, what are some important issues a consumer should know about generic drugs? In most people, the symptoms come and go. Some people go for months or years without symptoms remission. Then they will have a flare-up. About 5 to 10 out of 100 people with ulcerative colitis have symptoms all the time. How is ulcerative colitis diagnosed? Higher doses are associated with adverse GI effects. Syncope and hypotension have been reported with Amitiza in the postmarketing setting and a few of these adverse reactions resulted in hospitalization. Most cases occurred in patients taking 24 mcg twice daily and some occurred within an hour after taking the first dose or subsequent doses of Amitiza. Some patients had concomitant diarrhea or vomiting prior to developing the adverse reaction. Syncope and hypotension generally resolved following Amitiza discontinuation or prior to next dose, but recurrence has been reported with subsequent doses. Several cases reported concomitant use of medications known to lower blood pressure, which may increase the risk for the development of syncope or hypotension. Contact your doctor or health care provider right away if any of these apply to you. No signs of disease such as such as appendicitis or infection are seen. These are not all the side effects that may occur with the use of atorvastatin. Plasma concentrations of M3 were within the range of exposure from previous clinical experience with Amitiza. An may be present. Check for and possibly take out abnormal growths such as tumors in the belly or pelvis. Take Amitiza orally with food and water. If you at a moderate intensity -- meaning you have enough breath to talk but not sing -- for at least 2 ½ hours a week, you can further cut 20% to 30%. Many drugs can interact with atorvastatin. Below is just a partial list.
There have been two confirmed reports of overdosage with Amitiza. The first report involved a 3-year-old child who accidentally ingested 7 or 8 capsules of 24 mcg of Amitiza and fully recovered. The second report was a study patient who self-administered a total of 96 mcg of Amitiza per day for 8 days. The patient experienced no adverse reactions during this time. Additionally, in a Phase 1 cardiac repolarization study, 38 of 51 healthy volunteers given a single oral dose of 144 mcg of Amitiza 6 times the highest recommended dose experienced an adverse event that was at least possibly related to the study drug. Pfizer spokesman Bryant Haskins says that while Lipitor is among the world's safest drugs, it can -- rarely -- cause serious side effects. And the company, he says, makes these risks perfectly clear to doctors and to patients. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. In patients taking cyclosporine or the HIV protease inhibitors tipranavir plus ritonavir or the hepatitis C protease inhibitor telaprevir therapy with LIPITOR should be avoided. In patients with HIV taking lopinavir plus ritonavir, caution should be used when prescribing LIPITOR and the lowest dose necessary employed. In patients taking clarithromycin, itraconazole, or in patients with HIV taking a combination of saquinavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, or fosamprenavir plus ritonavir, therapy with LIPITOR should be limited to 20 mg, and appropriate clinical assessment is recommended to ensure that the lowest dose necessary of LIPITOR is employed. Clinical trials report few adverse reactions. Rare cases of contact dermatitis and anaphylaxis have been reported. An increased risk of kidney stones is possible in susceptible individuals. If any of these effects persist or worsen, tell your doctor or promptly. generic lamivudine order now shop
Take this medication by with or without food as directed by your doctor or other professional, usually once a day. It is very important to take it exactly as directed. not increase the dose, take it more frequently, or stop using it unless directed by your doctor. IBS symptoms over the past week compared to how you felt before you entered the study? Do NOT take more than the recommended dose without checking with your doctor. Doing so may cause an increase in the risk of severe side effects. Three-character codes are assigned only in situations when more than one reference listed drug of the same strength has been designated under the same heading. Two or more reference listed drugs are generally selected only when there are at least two potential reference drug products which are not bioequivalent to each other. If a study is submitted that demonstrates bioequivalence to a specific listed drug product, the generic product will be given the same three-character code as the reference listed drug it was compared against. These medicines can stop or reduce symptoms and prevent flare-ups. Atorvastatin is usually taken once a day, with or without food. Take the medicine at the same time each day. Your doctor may occasionally change your dose to make sure you get the best results. Atorvastatin is used in adults and children who are at least 10 years old. Since this drug can be absorbed through the and and may harm an unborn baby, women who are or who may become pregnant should not handle this medication or breathe the dust from the tablets. clavaseptin
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Each soft gel capsule contains 8 mcg of lubiprostone. Some MEDICINES MAY INTERACT with Lipitor. You will be asked to sign a consent form that says you understand the risks of the test and agree to have it done. gemfibrozil order now online mastercard
Older adults may be at greater risk for bleeding while using this drug. Take Lipitor by mouth with or without food. Pfizer is a WebMD sponsor. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.
Check the Rx Outreach website for the exact price and most current medication list. Jonathan Sackner Bernstein, MD: Well the first step that is recommended in any of the standard guidelines is lifestyle modifications, so that focuses on changing your diet, losing weight, exercising, and studies have shown that those approaches can have an effect if you're someone who can really adhere to that type of program, that type of lifestyle, which is not easy for most of us. But the amount of the effect is relatively modest, and so it is not surprising that doctors tend to go to the next step relatively frequently, which is the prescription of medicines such as statins. so these are medicines such as Lipitor, Zocor, Pravachol, Crestor. These are medicines that have been used by millions of people. They are not brand new medicines. The first one, Mevacor, is, was discovered back in the 80s and came out in the early 90s. There have been studies with thousands of people followed for several years. Huge databases of people followed since these drugs were on the market. So that we know, that not only do these drugs lower your LDL cholesterol, but for most of them, there have been studies that have shown that they also reduce your risk of a heart attack, stroke and dying early. Now you can find out that there have been side effects with these medicines as there are with any medicines, that's why they are taken under the supervision of a doctor. But if you look on balance with the amount of benefit you can get verses those potential risks which are very, very rare, that overall, for almost all of us who have high cholesterol, the risk benefit balance when you look at what you should do says that it's safer to take the medicine than to not take the medicine if your LDL cholesterol, your bad cholesterol remains high after all attempts at lifestyle modification.
ClC-2 by lubiprostone in the gastrointestinal tract. There is a possibility of a dose-dependent decrease in the efficacy of Amitiza in patients using diphenylheptane opioids. How will ulcerative colitis affect your life? Dosage is based on your medical condition, laboratory tests such as INR and response to treatment. Your doctor or other provider will monitor you closely while you are taking this medication to determine the right dose for you. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.